What is BMAC?

September 8, 2023


Bone marrow aspirate concentrate (BMAC) is a fluid that contains cells derived from the bone marrow, the soft, spongy substance found within the inner cavities of bones. This article will explore the process of obtaining bone marrow aspirate concentrate, its potential uses in tissue repair and healing, and its application in managing chronic pain.

Obtaining Bone Marrow Aspirate Concentrate

The first step in producing BMAC involves collecting bone marrow aspirate from a large bone, typically the pelvic bone. This is done through a minimally invasive procedure using a needle. The patient is usually under local anesthesia, sedation, or general anesthesia to minimize any discomfort. The aspirate is then processed using a centrifuge to separate the desired cells from other components of the bone marrow. Various processing methods are employed, which can impact the quantity and quality of the cells obtained, particularly stem and progenitor cells.

Mechanism of Action and Clinical Efficacy of BMAC

The mechanisms by which BMAC works within the body are still being studied. However, experts believe that is can modulate inflammation and potentially promote the formation of new tissue. Its clinical efficacy is being investigated in various applications.

Applications for BMAC in Tissue Repair and Healing

BMAC has shown promise in treating various conditions involving tissue repair and healing. Some of its potential applications include:

Bone Fracture Healing

BMAC has been used to aid in healing bone fractures that have not successfully fused back together. By introducing concentrated stem cells into the fracture site, BMAC may enhance the body’s natural healing processes and promote faster and more efficient bone healing.

Wound Healing

It has also demonstrated potential in improving wound healing. By harnessing the regenerative properties of stem cells, BMAC may accelerate the healing process, reduce scarring, and enhance tissue regeneration in chronic or non-healing wounds.

Cartilage Repair and Regeneration

BMAC has been explored as a potential treatment for cartilage damage and degeneration. By delivering a concentrated source of stem and progenitor cells to the affected area, bone marrow aspirate concentrate may help stimulate the growth of new cartilage tissue, offering a non-surgical option for individuals with cartilage injuries or osteoarthritis.

Osteonecrosis Treatment

Osteonecrosis, a condition characterized by bone death, can be challenging to treat. However, BMAC has shown promise in promoting the regeneration of bone tissue in osteonecrotic lesions. By introducing concentrated cells to the affected area, this therapy may help restore blood flow and facilitate the repair and regeneration of the damaged bone.

Tendon Function Improvement

BMAC can potentially improve tendon function by promoting tissue repair and regeneration. Tendons are prone to injuries and can be slow to heal. By harnessing the regenerative properties of stem cells, BMAC may aid in tendon healing and restore optimal function.

Osteoarthritis Management

BMAC has been investigated as a potential treatment for osteoarthritis, a degenerative joint disease characterized by the breakdown of cartilage. By introducing concentrated stem cells to the affected joint, BMAC may help stimulate cartilage regeneration and reduce inflammation, potentially offering relief from pain and improving joint function.

Delaying Disease Progression

In the case of chronic conditions such as arthritis, BMAC may potentially delay disease progression. By modulating inflammation and promoting tissue repair, BMAC may help slow down the degenerative processes associated with chronic joint diseases.

Utilizing BMAC for Chronic Pain Management

In addition to its applications in tissue repair and healing, bone marrow aspirate concentrate has garnered interest as a potential treatment for chronic pain. The regenerative properties of stem cells found in BMAC may be able to modulate pain signals and promote healing in damaged tissues, offering a non-invasive alternative to traditional pain management methods. While research in this area is still ongoing, early studies have shown promising results in using BMAC for chronic pain conditions such as osteoarthritis, tendinopathies, and low back pain.


Bone marrow aspirate concentrate (BMAC) holds great potential in the field of regenerative medicine. Obtained through a minimally invasive procedure, BMAC contains cells that can aid in tissue repair and healing. Its applications range from bone fracture healing to cartilage regeneration and osteoarthritis management. Additionally, BMAC shows promise in the management of chronic pain conditions. As research continues to unfold, BMAC may offer new avenues for treating a variety of ailments and improving patients’ quality of life.

To learn more about the uses of BMAC, contact the team at Integrative Spine & Sports using the form below.

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